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          Description


          Arthritis means inflammation of the joints. This unpleasant disease is extremely widespread among people older than 40 years. However, there are some types of arthritis which have peculiar manifestation in childhood and adolescence. That is why it is very important to get a good medicine which is able to struggle with this terrible disease.

          One of the most effective remedies from arthritis is Arava. An active component of this medicine is leflunomidis. It is a basic remedy for treatment of adult patients who suffer from active arthritis. It is able to reduce symptoms and damage joints setback, and it can cope with an active severe form of psoriatic arthritis.

          Rules of Intake

          The treatment should begin with a first single oral dose of 100 mg, and it should be taken during three days. Then the recommended dose for threatment of rheumatoid arthritis is decreased from 10 mg to 20 mg one time day, for psoriatic arthritis – 10-20 mg once a day. The positive therapeutic effect usually becomes evident after 4-6 weeks. The result can last up to 4-6 months.

          However, there are no recommendations as for the dosage of the remedy for patients suffering from mild form of renal insufficiency. It does not require the dose adjustment for the patients elder than 65 years. Tablets should be swallowed together with drinking a plenty of water. Food intake hasn’t got any effect on the level of absorption of leflunomide.

          Contraindications and Precautions

          People shouldn’t take Arava if they:

          bullet_ball_blue Suffer from impaired liver function;
          bullet_ball_blue Have severe immunodeficiency (for instance, AIDS);
          bullet_ball_blue Have significant disorders of the bone marrow hematopoiesis, or serious anemia, severe leukopenia or thrombocytopenia according to other reasons (which are other than rheumatoid arthritis);
          bullet_ball_blue Suffer from severe, uncontrolled infections;
          bullet_ball_blue Have moderate or even severe renal insufficiency (it is not recommended because of small experience of researches);
          bullet_ball_blue Suffer from severe hypoproteinemia (for instance, nephrotic syndrome);
          bullet_ball_blue Are pregnant or breastfeeding.

          Arava should not be taken by people with hypersensitivity to leflunomide or some other components of the remedy.

          Pay attention to the following recommendations:

          bullet_ball_blue Arava can be prescribed to patients only after professional careful medical examination:
          bullet_ball_blue Before you begin the treatment with Arava, you should learn the possibility of side effects when using by patients who were previously treated with other basic medicine for treatment of severe rheumatoid arthritis, which have hepato- and haematological effects;
          bullet_ball_blue Arava pills are not recommended for usage by patients of the age younger than 18, because information about its effectiveness and safety is not available.

          If you take Arava according to the prescription you will see positive results without side effects.

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